Chemical Screening Center
UCSC's Chemical Screening Center houses high-throughput screening(HTS) robotics that are used to search for biologically active compounds and siRNA targeted toward a variety of biological systems. Investigators can test up to 30,000 chemical compounds per day for biological function and/or usefulness in fighting diseases.
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Macromolecular Structure Function Core Facility
The Macromolecular Structure Function Core Facility (MSFCF) supports researchers with state of the art instrumentation, supplies, and expertise for the structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.
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Chemical Screening Center
UCSC's Chemical Screening Center houses high-throughput screening(HTS) robotics that are used to search for biologically active compounds and siRNA targeted toward a variety of biological systems. Investigators can test up to 30,000 chemical compounds per day for biological function and/or usefulness in fighting diseases.
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Macromolecular Structure Function Core Facility
The Macromolecular Structure Function Core Facility (MSFCF) supports researchers with state of the art instrumentation, supplies, and expertise for the structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.
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Mass Spectrometry
The mass spectrometry facility provides analytical support for the Department of Chemistry and Biochemistry and other academic departments at the University of California, Santa Cruz. The facility is to enhance the research, educational, and public service missions of the University.
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RESEARCH
Mechanism of Biofilm Formation
Surface Attachment
Biofilm Matrix Production and Assembly
Biofilm Dispersal
Regulation of Biofilm Formation
Cyclic Dimeric Guanosine Monophosphate (c-di-GMP) Signaling
Two-Component Signal Transduction Systems
Environmental Regulation of Biofilm Formation
Biofilm Properties
Hyperinfectivity
Type VI Secretion System
Biofilm Physiology
Antibiofilm Drug Recovery
Vibrio cholerae
Pseudomonas aeruginosa